Auragens has been treating, and seeing tremendous results, with our patients who are coming to us with cardiovascular issues. As we continue to track their follow ups, as the months pass, the results continue to be impressive. Since we have seen a significant increase in referrals and patients visiting us for these reasons, we felt it would be beneficial to share the reasons as to why the results have been so visible.
Mesenchymal stem cell (MSC) treatments are well suited in addressing various cardiovascular issues, primarily due to their regenerative and anti-inflammatory properties. To keep it straight forward let’s look at keyways MSCs positively impact cardiovascular health:
1. Tissue Regeneration and Repair
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MSCs are able to differentiate into cartilage, bone and adipose/fat tissue, in-vitro. In-vivo they halt their differentiation and secrete extracellular vesicles via paracrine signaling. This enables them to contribute to the regeneration of damaged heart tissue following events like heart attacks (myocardial infarction).
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They promote the formation of new blood vessels (angiogenesis) in ischemic tissues via the secretion of VEGF (vascular endothelial growth factor), improving blood flow and oxygen supply to the heart muscle.
2. Reduction of Inflammation
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MSCs release bioactive molecules that modulate the immune response and reduce inflammation in the heart, which is crucial in treating chronic inflammatory conditions such as heart failure or post-heart attack healing. By dampening inflammation, MSCs help create a more favorable environment for tissue repair.
3. Paracrine Effects
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MSCs release bioactive molecules that modulate the immune response and reduce inflammation in the heart, which is crucial in treating chronic inflammatory conditions such as heart failure or post-heart attack healing. By dampening inflammation, MSCs help create a more favorable environment for tissue repair.
4. Anti-fibrotic Effects
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MSC treatments help prevent or reduce fibrosis (scar tissue formation) in the heart. Excessive fibrosis can impair heart function after injury. By reducing fibrosis, MSCs help maintain the heart’s ability to contract and pump blood effectively.
5. Improvement of Heart Function
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Clinical studies and preclinical models have demonstrated that MSC therapy can improve heart function, including increasing the ejection fraction (the amount of blood the heart pumps with each beat) in patients with heart failure or those recovering from a heart attack.
6. Reducing Arrhythmias
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MSCs may also help reduce the risk of arrhythmias (irregular heartbeats), which are common after heart damage. By stabilizing the heart’s electrical system and reducing fibrosis, MSCs contribute to a more stable and healthy heart rhythm.
7. Myocardial Infarction (Heart Attack) Recovery
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In patients who have suffered a heart attack, MSCs have been shown to limit the size of the infarction and promote faster recovery of the heart muscle. This can prevent further deterioration and improve long-term cardiovascular outcomes.
In a one sentence recap, MSC stem cell treatments positively impact cardiovascular issues by promoting heart tissue regeneration, reducing inflammation and fibrosis, improving blood vessel formation, and supporting overall heart function.
Auragens is standing by and happy to discuss any nuance or details around a cardiovascular issue you or a loved one may be experiencing.
